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[ 2013-6-14 ]石榴素精華(Pomegranate Extract)可防治乳癌
編輯:補健Diy | 點擊率:922 次
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石榴素精華(Pomegranate Extract)可防治乳癌
現今全球每年超過400,000名婦女死于乳腺癌。從統計所得其中大約有75 %乳腺癌患者是由於雌激素過多所引起,這意味著患者她們可能曾經進服過雌激素。
美國癌症預防研究中心發表一篇有關石榴 (Pomegranate)的報告,原來石榴果內石榴精華(Pomegranate Extract)能"抑制"女性體內會引發乳癌的酵素 (Aromatase), 這個酵素會讓雄激素轉化成為雌激素,一旦雌激素的水平增加時,患乳癌的風險會隨著會增加。
美國加利福尼亞城市癌症研究員Shiuan Chen在電視專題訪問中也認為在石榴果內石榴精華(Pomegranate Extract)約有10種天然植化素(phytochemicals)能抑制Aromatase酵素,和防止癌症發生。
基於抑制病人的瘤腫擴散和防止曾經患乳腺癌婦女復發,醫生會為病人處方抗雌激素藥物,以圖維持雌激素在安全的水平以下。
然而Shiuan Chen認為這些石榴素精華(Pomegranate Extract)未必強效如真正的藥物可以作為治療之用,此物應用於"預防"多於"治療",而在治療時也不能代替抗雌激素等藥物。
http://new.radiousa.com/news/articles/2010/jan/05/pomegranate-compounds-may-ease-breast-cancer-risk/
By JoAnne Allen
WASHINGTON (Reuters) - Enzyme-blocking chemicals in pomegranates may reduce the risk of estrogen-fueled breast cancers, U.S. researchers said :
An acid found in pomegranates appears to block aromatase, an enzyme that converts androgen to estrogen, a hormone that plays a role in the development of breast cancer, the researchers wrote in the journal Cancer Prevention Research.
"We identified some of these chemicals in pomegranates that actually have properties that can suppress aromatase," researcher Shiuan Chen, of the City of Hope cancer research and treatment center in Duarte, California, said in a telephone interview.
Many women who had had breast cancer take medicines called aromatase inhibitors -- such as Pfizer's Aromasin, Novartis' Femara and AstraZeneca Plc's Arimidex -- to keep estrogen from feeding tumors.
Chen and colleagues studied whether compounds, or phytochemicals, in pomegranates could suppress aromatase and ultimately block cancer growth. They found that 10 natural compounds in the fruit may potentially prevent estrogen-related breast cancer.
Chen said the compounds would not be a replacement for aromatase inhibitors.
"We do not recommend people start taking this as a replacement for the AI's," Chen said. "They (pomegranate compounds) are not as potent as the real drugs so we think that the interest probably is more on the prevention end rather than in a therapeutic purpose."
More than 400,000 women died from breast cancer globally every year. About 75 percent of breast cancers were estrogen-receptor positive, meaning they were fed by estrogen.
Previous research had shown that pomegranate juice was rich in antioxidants -- vitamins and other substances -- that might help prevent diseases such as cancer, heart disease and Alzheimer's disease. (Editing by Xavier Briand)